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OpportunityAnalyzer: Cystic Fibrosis - Opportunity Analysis and Forecasts to 2025

Market: Pharmaceuticals and Healthcare

Global, 209 pages report, published by GlobalData

April-2017

OpportunityAnalyzer: Cystic Fibrosis - Opportunity Analysis and Forecasts to 2025

Summary

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which codes for the CFTR protein. As a multisystem condition, CF patients show great heterogeneity in presenting clinical symptoms. CF mainly affects the respiratory and gastrointestinal tracts. Three classes of drugs have been used to for treatment in CF patie

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1.2 List of Figures
Figure 1: Global Sales for CF by Country/Region, 2015 and 2025 11
Figure 2: Classes of CFTR Gene Mutations in CF 21
Figure 3: 7MM, Diagnosed Incident Cases of CF, All Ages, Both Sexes, N, 2015-2025 (Based on Registry Data) 51
Figure 4:

1.1 List of Tables
Table 1: Cystic Fibrosis: Key Metrics in the Seven Major Pharmaceutical Markets 9
Table 2: Onset of CF by Approximate Age 18
Table 3: Classification and Criteria of the CFTR Gene Mutations in CF 20
Table 4: Symptoms of CF 22
Table 5: Risk Factors and Comorbidities of CF 26
Table 6: 7MM, Sources Used to Forecast the Diagnosed Incident Cases of CF (Based on
Registry Data) 30
Table 7: 7MM, Sources Used to Forecast the Diagnosed Prevalent Cases of CF (Based on Registry Data) 31
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1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 6
1.2 List of Figures 7
2 Cystic Fibrosis: Executive Summary 9
2.1 CF Transmembrane Conductance Regulator Modulators Expected to Drive Substantial Growth in the Cystic Fibrosis Market from 2015-2025 9
2.2 Licensing Activity and the Formation of New Partnerships Will Steer Small Companies to Continue Research of Novel Compounds 11
2.3 Marketed and Pipeline CF Transmembrane Conductance Regulator Modulators Will Provide Appropriate Treatm